Formulation of rectal suppositories containing diuretic drugs and their biopharmaceutical studies
نویسنده
چکیده
منابع مشابه
Formulation and physicochemical control of vaginal suppositories containing the essential oil from Cuminum cyminum L. fruits
Background: Vulvovaginal candidiasis, as a prevalent vaginitis, is developed by Candida albicans. Regarding to the high incidence of this fungal infection and the antifungal activities of Cuminum cyminum, the preparation of vaginal suppositories containing its essential oil, has been considered as the main goal of the present investigation. Materials and methods: The constituents of C. cyminum ...
متن کاملLornoxicam Suppositories: In-vitro Formulation and In-vivo Evaluation
The aim of the present study was to formulate lornoxicam into rectal suppositories as a new dosage form, to avoid its reported gastric irritation and to provide a rapid onset of action for children. Suppositories were prepared using fatty bases namely; witepsol H-15, suppocire AML, CM, witepsol E-75 and water soluble bases; mixtures of poly(ethylene glycol), PEGs, with different molecular weigh...
متن کاملEffect of Adjuvants on the Release Pattern of Suppositories Containing Paracetamol
There is a vast interest in the scientific community and drug industry to exploit various mucosal routes of delivering drugs, which are poorly absorbed after oral administration. Human rectum remains to be a relatively unexplored route of drug delivery despite its potential as a noninvasive route of drug administration. The presence of dense network of blood vessels has made the rectum an excel...
متن کاملPreparatiOn and eValuation Of dOuble-phased mucOadheSiVe
In an attempt to restrict drug absorption from suppositories to only the lower rectum, mucoadhesive lidocaine (LID) suppositories were prepared using WitepsolR H-15 as a base, and CarbopolR 934p (CP) and white beeswax (WAX) as additives. CP has a mucoadhesive property and WAX gives the suppositories stiffness. The suppositories containing 109{(, CP and 20% WAX stayed in the lower recta of rats ...
متن کاملSuppositories in anal disorders: a review.
INTRODUCTION Drug treatment for various ano-rectal conditions has been known since ancient times. Suppositories are one of the very feasible modes of administration for medication. MATERIALS AND METHODS Medline (1950-2006) was searched for all published reports about suppositories. This study sum up various suppositories used in proctological practice, which either are in vogue and have been ...
متن کامل